Introduction

Meta-omics methods aim to simultaneously analyse the entire multi-species potential and realised functional capacity of a biological sample — taxonomically and functionally characterising all organisms and their activity in a community.

The aims of this interest group are:

  1. Coordinating compatibility between existing and potential meta-omic nf-core pipelines
  2. Implementing semi-‘chaining’ of sequential pipelines
  3. Developing standard parameters for different sub-disciplines (e.g. microbiome analysis) for each pipeline
  4. Documenting usage of “primary” meta-omic pipelines (createtaxdb, ampliseq, eager, taxprofiler, mag, metatdenovo) followed by complementary analyses with “secondary” pipelines (e.g. funcscan, phageannotator, phyloplace, rnaseq, differentialabundance)
Diagram showcasing how nf-core pipelines can potentially be used for complementary and sequential analysis within meta-omics disciplines using a London Underground style 'tube map'

Other activities include:

  1. Benchmarking meta-omic pipelines using relevant datasets (e.g. CAMI2), or reads generated using #readsimulator
  2. Adding nf-tests to meta-omic pipelines
  3. Reducing functional redundancy between pipelines

Activities

The group holds monthly meetings with developers and users to identify and discuss the most relevant problems related to meta-omics with nf-core pipelines. Activities also include presentations and discussions from topic-experts, tutorials, workshops, and demo-days of nf-core pipelines.

You can find ideas and planned work on our GitHub project board, and browse past meeting notes on HackMD.

How to join

Join the nf-core Slack and find us in the #meta-omics channel.